Brandon Santini is a rising star in the contemporary blues harmonica scene, heralded for his passionate style and soulful songwriting. Hailing from the North Carolina Piedmont region but deeply entrenched in the Memphis music scene, Santini combines the down-home feel of traditional blues with a modern, energetic twist that has become a signature of his performances and recordings. Early in his career, he honed his craft as the lead vocalist and harmonica player for the band Delta Highway, which helped him gain initial recognition in the blues world.

After leaving Delta Highway, Santini embarked on a solo career, releasing "Songs of Love, Money, and Misery" in 2011, a collection that showcased his rich harmonica skills and his abilities as a songwriter. His follow-up, "This Time Another Year," released in 2013, received critical acclaim and nominations for Blues Music Awards, solidifying his reputation as a force within the blues scene. "Live & Extended!," released in 2015, captured the raw energy of Santini's live performances, demonstrating why he’s celebrated on stage. In 2019, he released "The Longshot," his latest studio album, which continued to explore his diverse range of blues stylings. His song "Don't Shake the Devil's Hand," competes as a standout track, reinforcing Santini’s commitment to authentic blues infused with a unique, modern flair. With a harmonica in his hand and a soulful voice, Brandon Santini continues to captivate audiences and carve out his place in the pantheon of blues greats.